Six, microcrystalline cellulose: microcrystalline cellulose (Microcrystalline cellulose, MCC) is a crystalline cellulose produced by the partial hydrolysis of cellulose. It has good compressible and strong binding force. The pressed tablet has greater hardness and can be used as the "dry binder" for the direct press of powder. The trade name of foreign products is Avicel, and there are several specifications according to the size of the particles. Domestic microcrystalline cellulose has been widely applied in China, but its quality needs to be further improved, and the product category needs to be enriched. In addition, 20% microcrystalline cellulose in tablets was disintegrated.
Seven, inorganic salts: mainly inorganic calcium salts, such as calcium sulfate, calcium hydrogen phosphate and medicinal calcium carbonate. Calcium sulphate is more commonly used, its properties are stable, odorless odorless, slightly soluble in water, and a variety of drugs can be compatible with a variety of tablets made of smooth appearance, hardness, disintegration are good, and no adsorption of drugs. Two water calcium sulfate is often used in the excipients of the tablets. However, attention should be paid to the interference of calcium sulfate to the absorption of some main drugs (tetracyclines).